2012;12(3):2208. YYYY Colgate-Palmolive Company. Besides, these findings of the current study could be related to previously conducted clinical trials indicating the better clinical effectiveness of Pro-argin than strontium acetate against air-blast and tactile stimulus after three days and one week of application [30, 31]. Plus it has the freshness you trust from Colgate! We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. Trials. I am interested to hear you guys opinion and thought about it. Network meta-analysis on the effect of desensitizing toothpastes on dentine hypersensitivity. Nachar Sinus Rinse System, 4pcs Professional Baby Nasal Irrigator Portable Infant Nose Cleaner Quick Rinse Device All Natural Relief - BPA Free More Convenient. Lai et al. The prime focus of treatment nowadays is based on the exploration of novel materials to remineralise the exposed tubular endings and mimic and restore the structure of the dentin [11]. If symptoms persist, talk to your healthcare professional. The probable reason for variations between this clinical trial and previously conducted studies could be attributed to racial or ethnic differences between the conducted trials. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. and Ayad et al. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. [10] examined the evidence for strontium acetate and Pro-argin in 2018, and their findings depicted low quality of evidence for strontium acetate on the Grading of Recommendations, Assessment, Development, and Evaluations system (GRADE). Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. 2013;41:S317. In addition, patients were educated regarding the cause of the disease for prevention and awareness of oral hygiene measures, brushing techniques, and dietary influences in DH. Pashley D. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. It improves gum health and helps reduce factors that contribute to gum recession, a leading cause of tooth sensitivity. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. 2017;62(2):18691. Follow the directions for use. Dziki unikalnej formule Pro-Argin z arginin, wzmacnia szkliwo zbw i tym samym staj si one bardziej odporne na dziaanie kwasw. Ingredients *Calcium carbonate *Water 2020;99(5):51422. The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH. Providing effective solutions for this prevalent condition is a priority for every dental professional, and Colgates Pro-Argin technology is helping dentists lead the way. Colgate Sensitive Instant Relief Repair & Prevent tandkrm ger dig kliniskt bevisad lngvarig lindring mot ilningar i tta veckor nr du anvnder den tv gnger om dagen. Samueli A, Hill R, Gillam D. Bioactive glasses in the management of dentine hypersensitivity: a review. Gentle whitening formula. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. 0:00 / 0:30 Colgate Sensitive Pro-Relief Challenge Advert April 2012 178,990 views Mar 29, 2012 Take the Colgate Sensitive Pro-Relief Challenge to Show more 15 Dislike Share. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 A meta-analysis by Matranga et al. A systematic review. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. 2017;2017:2. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). 1). The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. A toothbrushing demonstration model from Nissin Company specification [PE-ORT002] was used to explain to the study participants about applying OTC dentifrices for one minute with the participant's finger. The statistician was also kept blinded. Favaro Zeola L, Soares PV, Cunha-Cruz J. Find products and services. 1):8A-15A. Can be used after the Colgate Sensitive Pro-Relief Desensitizing Paste. Ayad F, Ayad N, Zhang YP, DeVizio W, Cummins D, Mateo LR. Am J Dent. OTC dentifrices were applied and massaged gently with the applicator on at least two sensitive teeth per subject at two different sites, including cementoenamel junction and exposed dentinal surface, by the doctor in the office during the first visit. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. With the exclusive Pro-Argin formula, it provides instant* and lasting** relief by plugging the channels to block tooth sensitivity. The second objective of the current study was to directly compare the clinical efficacy of FCPS, Pro-argin technology, and strontium acetate-based dentifrices due to their similar mode of action and tubular occluding potential in managing DH [36, 37]. 1997;24(11):80813. Hence, the effectiveness of clinically available formulations of FCPS in OTC dentifrices needs further exploration for the permanent management of DH. SA was the principal investigator and has contributed to design, data acquisition, analysis, and interpretation, and drafted the manuscript. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. 1997;24(11):80813. (US). Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. statement and In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. Zinc helps strengthen gums and prevent gum recession a key cause of sensitivity1,2,3. 2009;22:3A-7A. Lavender SA, Petrou I, Heu R, Stranick MA, Cummins D, Kilpatrick-Liverman L, et al. 2017;457:2530. Follow the directions for use. J Clin Dent. Colgate Sensitive Pro Relief Instant Relief, Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. The Gum Health Physical is a new interactive digital tool you can use to quickly evaluate your patients in-office, and give them a personalized report they can use at home. 2010;21(2):428. Apotekets varuid 29483 Varunummer 207000 Kategori Tandkrm, Ilningar i tnderna Varumrke Get the best deals for COLGATE Sensitive Pro Relief Complete Protection Toothpaste 110g. The authors declare that they have no competing interests (financial and non-financial) related to the article. Oral dentifrices have been marketed extensively for pain relief in one minute after topical application on sensitive teeth, with the claims of several dentists recommending the formulations containing Pro-argin and 8% strontium acetate. Pessoa, Loretto et al. Felix J, Ouanounou A. Dentin hypersensitivity: etiology, diagnosis, and management. A total of 140 participants were initially enrolled and randomised into the four treatment arms, with thirty-five in each group. [22] reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. who examined FCPS and Pro-argin formulations in 2018. Learn more about caries in children from the resources provided on this page. Comparative evaluation of desensitizing efficacy of dentifrice containing 5% fluoro calcium phosphosilicate versus 5% calcium sodium phosphosilicate: a randomized controlled clinical trial. Colgate Sensitive Pro-Relief Original Toothpaste This toothpaste gives you the freedom to forget about tooth sensitivity. Martins CC, Firmino RT, Riva JJ, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. Pessoa OF, Loretto SC, Maia LC. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. Colgate Sensitive Pro Relief Whitening Toothpaste 75ml tube (Pack of 4) Instant and Lasting Relief Clinically Proven with Active Ingredients We have a surprise for you Find out all personalised promo codes that you are eligible for. Clin Cosmet Investig Dent. Customers also search toothpaste colgate sensitive colgate enamel colgate pro relief colgate pain relief The current study outcomes showed significant decrease in pain scores of air-blasts and water jet stimulated DH with FCPS based dentifrices compared to Pro-argin and 8% strontium acetate after two, four, and six weeks subsequently, as depicted in Tables 4 and 5. Google Scholar. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. These ingredients resulted in rapid fluorapatite crystallisation at exposed tubular ends of dentin [12]. Dentine hypersensitivity (DH) is a chronic condition with acute, transient pain in non-carious teeth that originates in response to thermal stimuli such as hot or cold, chemicals like acidic or sweet or salt, and mechanical stimuli due to exposure to dentinal tubules without any apparent clinical disease [1]. Written informed consent was obtained with a signed agreement plan to visit for six weeks at interim efficacy intervals of day three, week two, week four, and week six. 4.2 5 0 221 221 Colgate Sensitive Pro-Relief Enamel Rebuild toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. Participants analyzed per group were more than thirty fulfilling the requirement of Holland's guidelines for conducting clinical trials for the management of DH [42]. All rights reserved. J Clin Dent 20 (2009), special issue 123-130, 2. Statistical Package for the Social Sciences software v.21.0. Dent Health Curr Res. Dentin hypersensitivity treatments work in one of two ways. I want to acknowledge the administrative faculty and staff assistants in the Department of Periodontology for facilitation in data collection. Size: 75ml (Approx.) Compend Contin Educ Dent. Tandkrmen remineraliserar tandemaljen fr att ge bttre motstnd mot syraattacker. 2009;20(1):106. This binds to the negatively charged dentine surface like a magnet. 2020;99(5):51422. Ashwini S, Swatika K, Kamala DN. See patient relevant information on Colgate.com. compared Colgate Sensitive Pro Relief to another leading brand that desensitizes with a 2% potassium ion formula. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. 4.4 5 0 198 198 Colgate Sensitive Pro-Relief Gum Therapy toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. This toothpaste really does not help at all with symptoms of sensitive teeth. BMC Oral Health 21, 498 (2021). 1. Helps restore natural whiteness of teeth. The findings agreed with another in vitro trial by Mahmoodi et al. Gently removes stains and helps restore the natural whiteness of your teeth. Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). Anvnd tv gnger dagligen. Pro-Argin showed a greater reduction in DH with mean scores of (1.340.68) (4.201.70) (3.052.17) followed by strontium acetate (1.570.81) (4.651.87) (3.751.97) on SCASS and VAS for mechanical and water jet stimuli, one minute after application. Colgate-Palmolive Company 2018. Pro-Argin Technology works through a natural process of dentin tubule occlusion that attracts arginine and calcium carbonate to the dentin surface to form a protective seal that provides instant relief.2 Part of ^Vs novamin/sodium fluoride technology and stannous fluoride/sodium fluoride technology (p<0.05). Colgate Sensitive Instant Relief Enamel Toothpaste with Pro-Argin technology to help seal and repair the sensitive areas of teeth. Gillam D, Talioti E. The Management of Dentine Hypersensitivity. 2009; 20 (Spec Iss): 1722. 4Intervention D denotes Colgate Total. Free postage. Ingredients *Calcium carbonate *Water 2019;46(12):11216. 2017;71:18. The findings have revealed that both statistically and clinically significant change in mean scores of DH was observed with Pro-argin and 8% strontium acetate with p<0.05 relative to baseline for immediate and sustained relief from DH using clinical parameters of SCASS and VAS. 2023 BioMed Central Ltd unless otherwise stated. For children 6-12 years of age, once a week or less frequently. Use regularly to enjoy long-lasting relief from sensitivity*. Colgate Sensitive Pro-Relief It works by plugging the channels to block tooth sensitivity and with regular use. Another study by Hines et al. J Dent. A 3-day randomised clinical study investigating the efficacy of two toothpastes, designed to occlude dentine tubules, for the treatment of dentine hypersensitivity. J Clin Dent. Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. J Dent Res. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. Dent Health Curr Res. it is in a rubbish bin now. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. Table 3 demonstrates the percent change in the mean scores of DH on SCASS relative to baseline within the group for each treatment arm. . compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. Was this answer helpful? Tandkrmen innehller zink fr att strka tandkttet och frhindra att tandkttet drar sig tillbaka, vilket r en av de vanligaste orsakerna till att . J Oral Rehabil. Made by one of the best-known oral care companies in Australia, it has been clinically proven to provide both instantaneous and lasting relief from sensitivity, whilst also: Fighting cavities. Table 6 presents the change in the mean scores on VAS against waterjet stimulus from baseline to subsequent efficacy interval within each treatment arm. Manage cookies/Do not sell my data we use in the preference centre. In addition, they should be reproducible and clinically relevant to stimuli triggering pain in DH [35]. Desensitizing toothpastes depolarize the nerves to reduce pain signals to the brain, while occlusives block the dentin tubules to prevent painful stimuli affecting dentinal fluids. Dentine hypersensitivity. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. The price for Colgate Sensitive Pro-Relief is set at RM12.80 to avoid being categorized at RM13.00. Am J Dent. Akber A, Ali NS, Shabbir S, Wahid U, Farooqui WA. Builds a protective barrier that acts like . Dentine Hypersensitivity. With regular use, it creates a long-lasting protective barrier that acts as a seal against sensitivity. Grnberg C, Bauer F, Crispin A, Jakob M, Hickel R, Draenert ME. 1. Colgate Sensitive Pro-Relief toothpaste is a revolutionary and one-of-its kind remedy that can provide consumers suffering from Sensitivity the much needed instant and long lasting relief . Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste with Pro-Argin Technology and Zinc. Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Colgate Sensitive Pro-relief Instant Relief. [16] in a systematic review in 2015. Arshad, S., Zaidi, S.J.A. J Clin Dent 2009; 20 (Spec Iss): 17-22. 2019;88:103170. Layer T, Hughes N. Evidence for the efficacy of an 8% strontium acetate dentifrice for instant and lasting relief of dentin hypersensitivity. The second null hypothesis was that mean scores for pain due to DH among different treatment groups for sustained relief remains the same, and it was considered to be rejected at a p value0.05. The makers of Colgate Sensitive Pro-Relief and its rival, Sensodyne Rapid Relief, have been dobbing each other into the health regulator over advertising claims that the toothpastes give users "instant" relief to pain from sensitive teeth. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily Written consent was obtained from all participants to participate in the six-week clinical trial. The secondary objective of the study was to compare the clinical efficacy of Pro-argin, strontium acetate, and FCPS for immediate and sustained treatment response in DH that was measured on SCASS as a primary outcome measure and VAS as secondary outcome measure at efficacy intervals of one minute, day-three, week two, four and six. Colgate Tandpasta Sensitive Instant Relief Whitening. J Clin Periodontol. Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. However, the manufacturers of the tested dentifrices were acknowledged in the study [34], so information bias wasexpected in the conducted trial. Get the freedom to forget about tooth sensitivity with Colgate Sensitive Pro-Relief Complete Protection Toothpaste. KruskalWallis test was used to compare treatment groups. Both treatments showed clinically and statistically significant (p<0.001) relief in pain due to DH relative to baseline on immediate post-treatment observation, as shown in Table 3. Springer Nature. Dentine tubule occlusion by novel bioactive glass-based toothpastes. 2015;42(2):13141. The datasets analysed during the current study are available from the corresponding author on reasonable request. Effectiveness of dentifrices with new formulations for the treatment of dentin hypersensitivitya meta-analysis. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. Toothpaste doesn't only clean your teeth; we have products to help with a variety of tooth issues like sensitivity and more. J Oral Sci. WHAT IS Colgate SENSITIVE INSTANT Relief Repair & Prevent? Plus it has the freshness you trust from Colgate! SJAZ has contributed to the conception, design, interpretation of results and critically revised the manuscript. Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. 3. Mintsmak. Baseline scores were recorded to measure the intensity of pain due to DH on SCASS with scores2 [22] against air blast stimulus with a triple syringe of the dental unit and on a linear VAS of 10cm length with scores4cm [23], against mechanical stimulus with a dental probe and water jet stimulus with a triple syringe. Ingredients *Potassium Nitrate Therefore, the first null hypothesis was that mean scores for pain due to DH among different treatment groups for immediate relief remain. Product Information. A study evaluating the efficacy of strontium acetate relative to arginine-based dentifrices was conducted by West et al. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. Colgate-Palmolive Company 2018. However, FCPS formulation showed 1% more improvement than Pro-argin and 7% more than strontium acetate-based dentifrices. Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG. Read our disclaimer for details. Colgate Sensitive Pro Relief Multi Protection, offering all of the above benefits in one convenient formula. Exclusive Pro-Argin formula. in 2019 using BioMin F and Pro-argin. It has stannous fluoride as an active ingredient. A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with DH and equally randomized into four groups with parallel treatment assignment of FCPS, Pro-Argin, 8% strontium acetate, and sodium fluoride-based OTC dentifrices, and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (SCASS) and visual analogue scale (VAS) at interim efficacy intervals of one minute, three days, two, four, and six weeks, subsequently. 1 Nathoo et al. J Clin Dent. Docimo R, Montesani L, Maturo P, Costacurta M, Bartolino M, DeVizio W, Zhang YP, Cummins D, Dibart S, Mateo LR: Comparing the Efficacy in Reducing Dentine Hypersensitivity of a New Toothpaste Containing 8.0% Arginine, Calcium Carbonate, and 1450 ppm Fluoride to a Commercial Sensitive Toothpaste Containing 2% Potassium Ion: An Eight-Week Clinical Study in Rome, Italy. ClinicalTrial.gov: National Library of Medicine (US). * *With continued use twice a day Prevents sensitivity from coming back* *With continued use twice a day can help prevent sensitivity from coming back. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. 2017;30(4):2216. volume21, Articlenumber:498 (2021) Colgate Sensitive Pro-Relief Whitening Toothpaste provides clinically proven instant and lasting relief for sensitive teeth. However, Pro-argin showed more clinical improvement in air blast and mechanically stimulated DH compared to 8% strontium acetate, as shown in Tables 4 and 5. Provides 24/7 sensitivity protection. J Dent Res. Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. Nathoo S et al. Grading of Recommendations, Assessment, Development and Evaluations. The burden of dentine hypersensitivity. Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults. Colgate Sensitive Pro Relief offers a solution that is clinically proven to relieve sensitivity pain. *with direct application and daily brushing. Thank you for your feedback. Naturally, the researchers wondered whether it could help shield a person from acquiring the virus. The treatment difference between Pro-argin and 8% strontium acetate was not statistically significant with a p>0.05 for immediate and sustained pain relief in DH and statistically significant relative to control on all clinical parameters of the SCASS and VAS. Participants were randomly allocated to four treatment arms and randomly assigned with OTC dentifrices having FCPS, Pro-argin, strontium acetate, and sodium fluoride (NaF) with an allocation ratio of 1:1:1:1. Nathoo S, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR: Comparing the efficacy in providing instant relief of dentine hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride and to a control toothpaste with 1450 ppm fluoride: A three-day clinical study in New Jersey, USA. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. It remains a prevalent global disease with two different treatment modalities of home-care desensitisation with the over-the-counter (OTC) desensitisers such as potassium, Wilcoxon Signed-Rank Test was used to compute mean scores relative to baseline at each time point. To alleviate their tooth sensitivity problem, by using Colgate Sensitive Pro-Relief will give them lasting relief and they can drink ice water freely. The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. 2 Docimo et al. However, there is a substantial possibility that these fluoridated dentifrices can reduce DH. Zang P, Shaw D. A randomized clinical study to evaluate the efficacy of an 8%(w/w) strontium acetate dentifrice in providing relief from dentinal hypersensitivity. The sensitive toothpaste works in different ways to fight cavities, remove plaque, promote gum health and freshen breath. For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. A head-to-head comparative evaluation of these most effective bioactive agents, such as arginine and BAG-based desensitisers, was suggested by Martins et al. Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. California Privacy Statement, Provided by the Springer Nature SharedIt content-sharing initiative. This study investigated the relief from pain in DH in one minute after applying over the counter (OTC) dentifrices with Pro-Argin and strontium acetate and directly compared them with fluoro-calcium phospho-silicate (FCPS)-based dentifrices for immediate and sustained inhibition of painful stimulus provoking DH. J Dent. It also strengthens tooth enamel by helping rebuild weak spots. In our study, Pro-argin treatment revealed an immediate clinical reduction of 45.7% on SCASS, 56% on VAS used for mechanical stimuli, and 48.1% on VAS used for water jet stimuli in DH demonstrated in Tables 3, 5, and 6.